1. Question/objective sufficiently described? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2. Study design evident and appropriate? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
3. Method of subject/comparison group selection or source of information/input variables described and appropriate? |
1 |
2 |
2 |
2 |
1 |
1 |
2 |
1 |
1 |
1 |
2 |
4. Subject (and comparison group, if applicable) characteristics sufficiently described? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
2 |
1 |
2 |
5. If interventional and random allocation was possible, was it described? |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
6. If interventional and blinding of investigators was possible, was it reported? |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
7. If interventional and blinding of subjects was possible, was it reported? |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
N/A |
8. Outcome and (if applicable) exposure measure(s) well defined and robust to measurement/misclassification bias? Means of assessment reported? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
9. Sample size appropriate? |
2 |
1 |
2 |
2 |
1 |
1 |
2 |
1 |
2 |
1 |
1 |
10. Analytic methods described/justified and appropriate? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
11. Some estimate of variance is reported for the main results? |
2 |
2 |
2 |
1 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
12. Controlled for confounding? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
13. Results reported in sufficient detail? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
14. Conclusions supported by the results? |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
1 |
Total score |
21 |
21 |
22 |
21 |
20 |
20 |
22 |
19 |
21 |
19 |
20 |
Percentage |
95% |
95% |
100% |
95% |
91% |
91% |
100% |
86% |
95% |
86% |
91% |