Figure 3.
Antispike binding antibody (Bab) titers before and after messenger RNA (mRNA)-1273 booster. Scatterplot of antispike Bab titers before and after mRNA-1273 booster. All participants reached a substantial post-mRNA-1273 boost Bab titer, ranging between 2,570 and 1,380,384 BAU per milliliter (2.73 log10 range), and this was regardless of the pre-mRNA-1273 boost Bab titer, previous infection, or the timing of the previous infection (before or after a two-dose CoronaVac vaccination). Participants with a breakthrough infection post-CoronaVac (vaccinated-infected) had a higher pre-mRNA-1273 boost Bab titer than those infected before CoronaVac (infected-vaccinated) and the naive-vaccinated participants. Post-mRNA-1273 boost Bab titers were in the same range for all three subgroups. BAU = binding antibody units.