Table 5.

Standardized effect size: morphine comparator arms vs placebo.

Study	Primary endpoint	SES
Avenue	SPID24	0.76
Trevena P2	Modified SPID24	0.82
Trevena P3	% Responders, 24 h	0.52

SES, standardized effect size; SPID, Summed Pain Intensity Difference.