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. Author manuscript; available in PMC: 2023 Feb 4.
Published in final edited form as: Nat Rev Methods Primers. 2022 Aug 4;2:59. doi: 10.1038/s43586-022-00141-7

Fig. 3 |. Distribution of sample delivery techniques used for published SFX experiments resulting in PDB codes.

Fig. 3 |

Data up to December 2021. Of a total of 417, 71% used jets — 41% high viscosity extrusion (HVE), 30% gas dynamic virtual nozzles (GDVN) — 10% used drop-on-tape (DoT), 7% employed fixed targets or chips, 5% SF-ROX136 and 5% MESH224,225. Jet-type techniques are shown in shades of blue. Other includes MESH (~ 5%), free droplets and segmented flow. Conceptually, SF-ROX and MESH can be considered to belong to fixed target and injection sample delivery, respectively. However, both approaches have distinct and unique features: SF-ROX136 uses very large single crystals and MESH uses high electric fields.