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. Author manuscript; available in PMC: 2023 Feb 4.
Published in final edited form as: Nat Rev Methods Primers. 2022 Aug 4;2:59. doi: 10.1038/s43586-022-00141-7

Table1.

Overview of XFEL facilities and instruments for SFX.

Facility beamline Beam parameters Photon energy, repetition rate, pulse length, photons per pulse, focus Detector pixels, pixel size, frame rate, distance Sample delivery options Sample environ ment Pump laser pulse duration, wavelength, timing Remarks
keV Hz fs ph/pulse μm 106 μm2 Hz mm fs nm fs
LCLS, Menlo Park, USA, 2009
MFX 5 – 24 120 30 – 100
or
<10
1·1012
or
1·1011
3×3 (2×2) ePix10K-2.1M SF-ROX with sample change robot
MESH, GDVN, HVE, DoD, fixed targets
90–278 K
Ambient pressure
Helium available, humidity controlled
50 – 150
< 8ns
410 – 2400
210 – 2200
δt0<200 spec. encod. Protein Crystal Screening (PCS) beam time available
Data analysis pipeline / support
Screening beam time available at SSRL synchrotron with matching sample delivery options.
Beamline website
2.1 100 × 100 120 50 – 1500
Rayonix 340-XFEL
59 44 × 44
177 × 177
2.5
30
70 – 1100
CXI 6 – 10.5
or
10.5 – 25
120 30 – 100
or
<10
1·1012
or
1·1011
0.1 or 1 Jungfrau MESH, GDVN, HVE, fixed targets Vacuum (10−5 Torr)
Ambient pressure
50 – 150
ns
410 – 2400
200 – 266
δt0<200 PCS available in parasitic mode
Data analysis pipeline and support
Beamline website
4 75 × 75 120 70 – 580
SACLA, Sayo, Hyogo, Japan, 2011
BL3 4–20 30 (60) <10 1011 >1 MPCCD SF-ROX, fixed targets, GDVN, HVE226 and DoD84 (in DAPHNIS chamber) 100K - RT
Helium at ambient pressure
30 200 – 2700 δt0 <7 Feasibility study beam time available.
Data analysis pipeline and support
Beamline details
4 50 × 50 60 50 – 150
BL2 4–15 30 (60) <10 1011 >1 MPCCD SF-ROX, GDVN, HVE226 and DoD (in DAPHNIS chamber) 100K - RT,
Helium at ambient pressure
5 ns 210 - 2600 Feasibility study beam time available.
Data analysis pipeline and support
Beamline details
4 50 × 50 60 50 – 150
SwissFEL, Villigen, Switzerland, 2019
Alvra 2 −12.4 100 - 4·1011 1.5 Jungfrau HVE, GDVN (user supplied) RT
Helium at 5·10−4 - 800 mbar
50 240 – 2500 - Data analysis pipeline and support
Beamline website
4 or 16 75 × 75 100 100
EuXFEL, Schenefeld (near Hamburg), Germany, 2017
SPB/SFX 6–15 1.1 MHz
or
4.5 MHz
~25 1.5·1012 3
or
<0.4
AGIPD GDVN, aerosol injection
HVE, fixted target at lower repetition rate (10 Hz)
Vacuum, 1·10−6 mbar typical, 1.10−4 mbar maximum
Ambient pressure at low rep rate (second interaction region)
4.5 MHZ Protein screening beamtime available
Data analysis pipeline and support: EXtra-xwiz automated pipeline in beta-testing.
Extra-xwiz documentation
Up-to-date parameters
15, 50 or 300 370 – 420 -
1 200 × 200 4.5 MHz 129–329 1.1 MHz
<100 420 – 2600 -
4.5 MHz
0.85 or 400 ps 1030 -
Up to 20 Hz
3–7 ns 210 – 2400 -
PAL-XFEL, Pohang, Korea, 2017
NCISFX 2.2 – 15 60 25 3·1010 (monochrom.)
or
1·1012 (pink)
5×5
or
2×2
Rayonix MX225-HS GDVN and HVE33,227, fixed targets RT
He at ambient pressure
40
7 ns (15Hz)
800/400/266
1064/532/355/266
δt0 < 20 Protein screening beamtime available
Beamline website
33 156×156
234×234
30
60
100 ~ 1000
Jungfrau
4 75 × 75 60 100 ~ 1000 -