Table 2.
Association between remnant cholesterol and cardiovascular disease in young and later adults.
| Outcomes |
Remnant cholesterol, mmol/L |
Per 1 mmol/L increase |
P for trend |
Pinteraction |
|||
|---|---|---|---|---|---|---|---|
| <0.50 |
0.50–0.99 |
1.00–1.49 |
≥1.50 |
||||
| Age<40 years | |||||||
| Case, n (%) | 33(0.58) | 39(0.91) | 35(1.17) | 57(1.73) | |||
| Incidence rate, per 1000 person-y | 0.53(0.38–0.75) | 0.84(0.61–1.15) | 1.08(0.77–1.50) | 1.60(1.23–2.07) | |||
| Model 1 | Reference | 1.49(0.94–2.37) | 1.91(1.18–3.07) | 2.48(1.61–3.81) | 1.26(1.12–1.41) | <0.0001 | 0.0004 |
| Model 2 | Reference | 1.46(0.92–2.33) | 1.85(1.14–2.99) | 2.24(1.45–3.47) | 1.23(1.09–1.39) | <0.0001 | 0.0019 |
| Age≥40 years | |||||||
| Case, n (%) | 1454(7.33) | 1351(7.31) | 1131(7.19) | 2145(8.46) | |||
| Incidence rate, per 1000 person-y | 7.18(6.82–7.56) | 7.14(6.76–7.53) | 6.99(6.60–7.41) | 8.26(7.92–8.62) | |||
| Model 1 | Reference | 1.01(0.94–1.09) | 0.99(0.92–1.07) | 1.22(1.14–1.30) | 1.06(1.04–1.08) | <0.0001 | |
| Model 2 | Reference | 0.98(0.91–1.06) | 1.00(0.92–1.08) | 1.21(1.13–1.29) | 1.06(1.03–1.09) | <0.0001 | |
Model 1: adjusted for age and sex.
Model 2: further adjusted for body mass index, systolic blood pressure, diastolic blood pressure, education, income, smoking status, drinking status, physical activity, a history of hypertension, diabetes mellitus, and dyslipidemia, antihypertensive drugs, antidiabetic drugs, fasting blood glucose, and high sensitivity C-reactive protein.