Table 1.
Population demographics.
| CAD Risk Factors | Controls | CAD |
p-value |
|---|---|---|---|
| (t-test) | |||
| Number of participants | 115 | 229 | |
| Age (years) | 46.2 ± 12.3 | 65.3 ± 10.7 | <0.0001 |
| Male (n; %) | 34; 29.6 | 170; 78.6 | <0.0001 |
| Weight (Kg) | 76.7 ± 16.6 | 86.1 ± 19.5 | <0.0001 |
| Height (cm) | 167.2 ± 9.3 | 171 ± 9.5 | 0.0005 |
| BMI (Kg/m2) | 27.5 ± 5.9 | 29.1 ± 6.4 | 0.0188 |
| Systolic BP (mmHg) | 124 ± 20 | 131 ± 24 | 0.0111 |
| Diastolic BP (mmHg) | 76 ± 14 | 72 ± 12 | 0.0142 |
| Total Cholesterol (mmol/L) | 5.0 ± 1.0 | 4.2 ± 1.3 | <0.0001 |
| LDL Cholesterol (mmol/L) | 2.9 ± 0.9 | 2.3 ± 1.0 | <0.0001 |
| HDL Cholesterol (mmol/L) | 1.6 ± 0.4 | 1.2 ± 0.5 | <0.0001 |
| TG (mmol/L) | 1.1 ± 0.6 | 1.8 ± 2.1 | <0.0001 |
| CRP (mg/L) |
2.5 ± 3.4 |
12.0 ± 31.2 |
0.0020 |
| n; % | p-value | ||
|
(Chi 2) | |||
| Hypertension | 15; 13.0 | 128; 55.9 | <0.0001 |
| Diabetes | 0; 0 | 44; 19.2 | N/A |
| Dyslipidaemia | 57; 49.6 | 134; 58.5 | 0.1157 |
| GFR <60 ml/min | 3; 2.7 | 45; 20.0 | <0.0001 |
| Arthritis | 6; 5.2 | 35; 15.3 | 0.0065 |
| Depression | 11; 9.6 | 43; 18.8 | 0.0267 |
| Employed | 104; 92.9 | 66; 33.3 | <0.0001 |
| Current smokers | 5; 4.4 | 42; 19.3 | 0.0002 |
| Ex-smokers | 45; 39.1 | 110; 50.4 | <0.0001 |
| Medications | % | % | |
| Statins | 8.69 | 73.45 | <0.0001 |
| Anti-hypertensive therapy | 11.30 | 75.78 | <0.0001 |
| Anti-platelet therapy | 6.08 | 67.84 | <0.0001 |
| Anti-angina therapy | 0.87 | 38.77 | <0.0001 |
| Diuretics | 2.60 | 24.67 | <0.0001 |
BMI, body mass index; BP: blood pressure; CAD, coronary artery disease, CRP, C-reactive protein; GFR, Glomerular filtration rate; HDL: high density lipoprotein; LDL, low density lipoprotein; TG, triglycerides.