Table 3.
Incidencea of carotid plaque according to Helicobacter pylori (H. pylori) infection status in the MN and MJ cohort and pooled multivariable-adjusted hazard ratios (HRs) for developing carotid plaques in participants with H. pylori infection.
| Participants | MN cohort |
MJ cohort |
Pooled HR (95%CI)b | Pooled HR (95%CI)c | ||
|---|---|---|---|---|---|---|
| H. pylori - | H. pylori + | H. pylori - | H. pylori + | |||
| All participants | 8.12 | 9.04 | 5.92 | 6.54 | 1.05 (1.02–1.09) | 1.04 (1.01–1.08) |
| Without self-reported cancer | 8.13 | 9.05 | 5.89 | 6.56 | 1.05 (1.02–1.09) | 1.04 (1.01–1.08) |
| Without self-reported cancer or peptic ulcer | 8.12 | 9.05 | 5.78 | 6.53 | 1.06 (1.02–1.09) | 1.04 (1.01–1.08) |
| Without missing value | 7.55 | 8.50 | 4.27 | 4.73 | 1.06 (1.02–1.11) | 1.05 (1.01–1.10) |
| Set 1-year lag | 8.09 | 9.00 | 5.69 | 6.27 | 1.05 (0.97–1.13) | 1.03 (0.95–1.12) |
Presented per 100 person–year.
Adjusted for age (<30, 30–39, 40–49, 50-59, 60–69, ≥70 year), sex (women, men).
Further adjusted for annual personal income (<0.1, 0.1–0.2, or ≥ 0.2 million), body mass index (<18.5, 18.5-23.9, 24.0-27.9, or ≥ 28 kg/m2), blood pressure (normal, prehypertension, or hypertension), blood glucose (normal, prediabetes, or diabetes), triglycerides (tertile), low-density lipoprotein cholesterol (tertile), high-density lipoprotein cholesterol (tertile), high-sensitivity C-reactive protein (tertile), and estimated glomerular filtration rate (tertile).