Table II.
Cutaneous and systemic symptoms of mpox infection at symptom onset and total duration of illness
| Symptoms | Total (N = 101) |
|---|---|
| Initial symptoms (day 0) | |
| Skin lesions or rash∗ | 55 (54.5%) |
| Intra-oral or throat lesions† | 1 (1.0%) |
| Lymphadenopathy | 3 (3.0%) |
| Fever | 16 (15.8%) |
| General malaise (fatigue, chills, myalgia) | 9 (8.9%) |
| Sore throat | 8 (7.9%) |
| Rectal pain | 7 (6.9%) |
| Ocular/Ophthalmic symptoms | 1 (1.0%) |
| Edema | 1 (1.0%) |
| Number of lesions at symptom onset | |
| 1 | 20 (19.8%) |
| 2-5 | 52 (51.5%) |
| 6-20 | 20 (19.8%) |
| 21-50 | 5 (5.0%) |
| Unknown | 4 (4.0%) |
| Anatomic site of mucocutaneous lesions | |
| Oral cavity | 11 (10.9%) |
| Tonsils | 3 (3.0%) |
| Throat | 0 (0%) |
| Soft palate | 1 (1.0%) |
| Total number of lesions – throughout duration of infection | |
| 1 | 10 (9.9%) |
| 2-5 | 29 (28.7%) |
| 6-25 | 38 (37.6%) |
| 26-50 | 17 (16.8%) |
| 51-100 | 3 (3.0%) |
| 101+ | 1 (1.0%) |
| Edema location | |
| Peri-orbital | 2 (2.0%) |
| Face‡ | 8 (7.9%) |
| Perirectal/perianal | 4 (4.0%) |
| Scrotal/penile | 12 (11.9%) |
| Extremities | 4 (4.0%) |
| Symptoms during course of illness | |
| Skin lesions or rash | 99 (98.0%) |
| Intraoral or throat lesions | 15 (14.9%) |
| Fever | 65 (64.4%) |
| Chills | 21 (20.8%) |
| Myalgia | 18 (17.8%) |
| Arthralgia | 10 (9.9%) |
| Fatigue | 39 (38.6%) |
| Sore throat | 21 (20.8%) |
| Cough | 5 (5.0%) |
| Headache | 19 (18.8%) |
| Lymphadenopathy | 52 (51.5%) |
| Proctitis | 17 (16.8%) |
| Rectal pain | 16 (15.8%) |
| Penile edema | 5 (5.0%) |
| Other | 8 (7.9%) |
Patients also reported to have eye pain, abdominal pain and vomiting, conjunctivitis, penile pain, limb edema.
∗
Any location on the body including groin, anal/perianal or lips.
†
Specified as lesions inside mouth or in the throat.
‡
Includes the lips, excludes the eyes.