TABLE 2.
The hematological profiles of COVID‐19 patients infected by the Omicron variant and control group as indicated
| Variable | Control group (1) | COVID‐19 with fever (2) | COVID‐19 with emergences (3) | p‐Value | |
|---|---|---|---|---|---|
| (n = 190) | (n = 170) | (n = 46) | 1 vs. 2 | 2 vs. 3 | |
| Male/Female | 101/89 | 75/95 | 22/24 | 0.092 | 0.739 |
| Age, year | 57 (34–73) | 59 (37–71) | 68 (57–80) | 0.603 | 0.024 |
| WBC, ×109/L | 9.6 (7.3–12.35) | 6.40 (4.80–8.30) | 6.75 (5.68–9.45) | <0.001 | 0.213 |
| Neutrophils, ×109/L | 7.21 (5.00–9.71) | 4.67 (3.28–6.10) | 4.96 (3.63–8.43) | <0.001 | 0.081 |
| Lymphocytes, ×109/L | 1.44 (0.94–2.04) | 0.93 (0.60–1.40) | 0.77 (0.42–1.25) | <0.001 | 0.086 |
| Monocytes, ×109/L | 0.7 (0.48–1.0) | 0.67 (0.48–0.88) | 0.63 (0.45–0.89) | 0.354 | 0.613 |
| NLR | 4.6 (2.90–8.57) | 4.96 (2.78–8.10) | 6.99 (3.71–12.83) | 0.571 | 0.008 |
| MLR | 0.49 (0.31–0.75) | 0.72 (0.47–1.09) | 0.82 (0.44–1.62) | <0.001 | 0.194 |
| RBC, ×1012/L | 4.65 (4.14–5.06) | 4.58 (4.18–4.99) | 4.41 (4.00–4.70) | 0.647 | 0.03 |
| Hemoglobin, g/L | 138 (125–152) | 136 (123–148) | 136 (123–142) | 0.225 | 0.526 |
| Hematocrit, % | 41.6 (38.05–45.00) | 40.50 (37.20–44.25) | 40.00 (36.73–42.93) | 0.193 | 0.206 |
| MCV, fL | 89.9 (87.3–92.9) | 89.10 (86.30–91.33) | 90.65 (87.65–93.80) | 0.033 | 0.033 |
| MCHC, gL | 334 (326–342) | 333 (323–341) | 334 (329–345) | 0.348 | 0.078 |
| MCH, pg | 29.9 (29.2–31.0) | 29.70 (28.50–30.80) | 30.50 (29.45–31.53) | 0.055 | 0.001 |
| RDW, % | 12.4 (11.9–13.2) | 12.30 (11.90–13.20) | 12.25 (11.90–13.03) | 0.513 | 0.846 |
| Platelets, ×109/L | 200 (158–259) | 176 (145–227) | 202 (153–247) | 0.008 | 0.165 |
| PLR | 140.21 (105.34–204.43) | 184.12 (130.94–293.99) | 258.57 (157.59–449.65) | <0.001 | 0.018 |
| MPV, fL | 9.60 (8.90–10.30) | 9.80 (9.20–10.40) | 10.10 (9.60–10.60) | 0.016 | 0.157 |
| MPR | 0.048 (0.036–0.065) | 0.053 (0.042–0.069) | 0.050 (0.038–0.067) | 0.013 | 0.272 |
| CRP, mg/L | 24.19 (2.19–66.24) | 5.53 (0.98–13.29) | 4.67 (2.76–25.46) | <0.001 | 0.112 |
| SII | 998.35 (593.23–1868.21) | 823.38 (472.68–1702.68) | 1368.57 (682.35–2411.92) | 0.091 | 0.006 |
Note: Values are presented as median (interquartile range) for continuous variables. p‐values with statistical differences were shown in bold.
Abbreviations: WBC, white blood cell; NLR, neutrophil‐to‐lymphocyte ratio; MLR, monocyte‐to‐lymphocyte ratio; RBC, red blood cell; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red blood cell width distribution; PLR, platelet‐to‐lymphocyte ratio; MPV, mean platelet volume; MPR, mean platelet volume‐to‐platelet ratio; CRP, C‐reactive protein; SII, systemic inflammatory index.