Table 1.

Differential metabolites contributed to group classification.

Metabolites	Regulations (Model vs. Control)	FC	p-value
Malic acid	↓	0.31	0.007
Fumaric acid	↓	1.37	0.038
Citric acid	↓	0.7	0.003
Cis-Aconitic acid	↓	0.85	0.048
Heptadecanoic acid	↓	0.67	0.010
Nonadecanoic acid	↓	0.30	0.010
Hydrocinnamic acid	↓	0.31	0.028
4-Hydroxyphenylpyruvic acid	↓	0.05	0.038
p-Hydroxyphenylacetic acid	↓	0.73	0.049
2-Phenylpropionate	↓	0.50	0.050
Suberic acid	↓	0.79	0.028
Valeric acid	↓	0.46	0.050
Stearic acid	↓	0.34	0.050
Butyric acid	↓	0.14	0.002
Acetic acid	↓	0.72	0.043
Isobutyric acid	↓	0.47	0.030
L-Tryptophan	↑	11.31	0.021
l-Histidine	↑	4.31	0.031
l-Leucine	↑	1.29	0.0402
l-Glutamic acid	↑	3.03	0.012
l-Proline	↑	1.58	0.024
Glutathione	↓	0.69	0.037
3-Indoleacetonitrile	↓	0.54	0.05
Metabolites	Regulations (Model vs. GS)	FC	p-value
Citric acid	↓	0.76	0.046
Malic acid	↓	0.55	0.024
l-Glutamic acid	↑	1.30	0.028
Stearic acid	↓	0.23	0.010
Succinic acid	↓	0.69	0.023
Aconitic acid	↓	0.51	0.034
Heptadecanoic acid	↓	0.48	0.002
Pentadecanoic acid	↓	0.57	0.002
Hydroxypropionic acid	↓	0.26	0.028
Arachidic acid	↓	0.41	0.002
2-Phenylpropionate	↓	0.22	0.005
3-Indoleacetonitrile	↓	0.79	0.029
Butyric acid	↓	0.69	0.033
Tetracosanoic acid	↓	0.42	0.005
Valeric acid	↓	0.42	0.045
L-Tryptophan	↑	2.27	0.041
Behenic acid	↓	0.52	0.002