Table 2.
Acute CMR Findings Stratified According to Higher and Lower T1 in Infarcted and Noninfarcted Myocardium
| Acute CMR Findings (Median 2 d) | Patients (N = 219) | Infarct T1 |
Noninfarct T1 |
||||
|---|---|---|---|---|---|---|---|
| Higher T (≥1,300 ms) (87% of Cohort) | Lower T1 (<1,300 ms) (13% of Cohort) | P Value | High T1 (>1,250 ms) (46% of Cohort) | Normal T1 (≤1,250 ms) (54% of Cohort) | P Value | ||
| Acute LVEDVI, mL/m2 | 80 ± 17 | 81 ± 15 | 82 ± 19 | NS | 83 ± 17 | 78 ± 16 | 0.016 |
| Acute LVESVI, mL/m2 | 43 ± 13 | 44 ± 12 | 44 ± 16 | NS | 47 ± 14 | 39 ± 11 | <0.0001 |
| Acute LVEF, % | 47 ± 9 | 47 ± 9 | 47 ± 9 | NS | 44 ± 9 | 50 ± 7 | <0.00001 |
| Acute RVEDVI, mL/m2 | 65 ± 14 | 65 ± 14 | 67 ± 17 | NS | 63 ± 13 | 67 ± 15 | NS |
| Acute RVESVI, mL/m2 | 29 ± 10 | 29 ± 10 | 30 ± 12 | NS | 28 ± 9 | 30 ± 11 | 0.082 |
| Acute RVEF, % | 56 ± 8 | 56 ± 8 | 56 ± 9 | NS | 57 ± 9 | 56 ± 8 | NS |
| Acute AAR, % of LV mass | 41 ± 14 | 44 ± 13 | 35 ± 14 | 0.005 | 47 ± 13 | 36 ± 12 | <0.00001 |
| Acute IS, % of LV mass | 22 (13-33) | 24 (16-34) | 22 (13-29) | NS | 28 (16-38) | 20 (11-27) | <0.00001 |
| MVO, % of LV mass | 0.57 (0.00-1.19) | 0.86 (0.00-3.38) | 1.23 (0.00-6.31) | NS | 1.16 (0-5.22) | 0 (0-2.17) | 0.007 |
| MVO presence, % of patients | 52.8 | 57.9 | 59.3 | NS | 60.2 | 47.4 | 0.080 |
| IMH presence, % of patients | 52.3 | 58.8 | 56.0 | NS | 59.7 | 47.1 | NS |
| RV infarct, % of patients | 25.5 | 26.9 | 25.9 | NS | 26.2 | 24.7 | NS |
| Global T1, ms | 1,273 ± 50 | 1,287 ± 43 | 1,227 ± 29 | <0.00001 | 1,311 ± 38 | 1242 ± 36 | <0.00001 |
| Infarct T1, ms | 1,366 ± 68 | 1,384 ± 55 | 1,262 ± 36 | <0.0001 | 1,387 ± 62 | 1349 ± 69 | <0.00001 |
| Infarct T1 adjusted for large MVO, ms | 1,372 ± 67 | 1,389 ± 56 | 1,271 ± 33 | <0.00001 | 1,394 ± 59 | 1,352 ± 68 | <0.00001 |
| Noninfarct T1, ms | 1,245 ± 43 | 1,253 ± 39 | 1,217 ± 38 | <0.00001 | 1,283 ± 28 | 1,214 ± 25 | <0.00001 |
| Remote T1, ms | 1,203 ± 46 | 1,209 ± 45 | 1,182 ± 43 | 0.003 | 1,232 ± 41 | 1,179 ± 34 | <0.00001 |
Values are mean ± SD, median (IQR), or %. Values in bold indicate a P value <0.05.
AAR = area at risk; CMR = cardiac magnetic resonance; IMH = intramyocardial hemorrhage; IS = infarct size; LV = left ventricle; LVEDVI = indexed left ventricular end-diastolic volume; LVEF = left ventricular ejection fraction; LVESVI = indexed left ventricular end-systolic volume; MVO = microvascular obstruction; NS = nonsignificant P value; RV = right ventricle; RVEDVI = indexed right ventricular end-diastolic volume; RVEF = right ventricular ejection fraction; RVESVI = indexed right ventricular end-systolic volume.