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. 2023 Jan;16(1):46–59. doi: 10.1016/j.jcmg.2022.09.015

Table 6.

Comparisons of Models of Conventional CMR Indices With and Without Novel T1 Indices in Predicting Long-Term MACE After STEMI

Model Predictors C-statistic Integrated Brier Score Comparison of Models
Net Reclassification Index
Integrated Discrimination Improvement Index
Chi-Square Difference P Value Index P Value Index P Value
A Acute LVEF
MVO presence
Infarct size
0.67 ± 0.07 0.076 N/A
B Acute LVEF
MVO presence
Infarct size
Infarct T1
Noninfarct T1
0.76 ± 0.06 0.064 Model A vs B
15.52 <0.001 39.8% (95% CI: 12.2%-64.4%) 0.007 16.4% (95% CI: 6.8%-30.9%) <0.001
C Acute LVEF <40%
MVO presence
Infarct size
0.69 ± 0.06 0.075 N/A
D Acute LVEF <40%
MVO presence
Infarct size
Infarct T1
Noninfarct T1
0.77 ± 0.06 0.064 Model A vs D
17.32 <0.001 50.4% (CI 17.7%-68.3%) 0.013 18.7% (CI 6.5%-32.4%) <0.001
Model C vs D
13.21 0.001 42.3% (CI 1.4%-66.2%) 0.027 16.1% (CI 4.7%-30.1%) <0.001

Comparison of the ability of models with conventional CMR indices (A, C) and models with T1 indices added (B, D) to predict clinical outcomes.

C-statistic = concordance statistic; MACE = major adverse cardiac events; N/A = not applicable; other abbreviations as in Tables 1 and 2.