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. 2022 Aug 26;34(1):67–78. doi: 10.1007/s00192-022-05308-0

Table 2.

'Cured' along with any further treatment required by 6 years

Trial 1: Native tissue repair vs polypropylene mesh inlay Trial 2: Native tissue repair vs biological xenograft
Native tissue Mesh inlay Eff. size 95% CI p-value Native tissue Biological xenograft Eff. size 95% CI p-value
6-Year outcomes
No. of women at 6 years N = 272 N = 277 N = 238 N = 250
Cured-no feeling of something coming down at 6 years, no prolapse surgery by 6 years, no pessary use at 6 years 53.7% 144 268 54.7% 150 274 1.02 [1] 0.88 to 1.19 0.797 51.5% 120 233 49.4% 122 247 0.99 0.83 to 1.18 0.892
Number of women having any new prolapse operation within 6 years (cumulative) 12.0% 32 266 10.3% 28 271 0.87 0.54 to 1.40 0.572 11.7% 27 231 11.8% 29 245 1.00 0.61 to 1.63 0.995
Number of women having any mesh removed within 6 years (cumulative) 1.6% 4 255 8.4% 22 263 5.24 1.84 to 14.96 0.002 1.4% 3 221 0.9% 2 231 0.59 0.10 to 3.48 0.562

Footnotes:

1. Concomitant incontinence procedure and concomitant upper prolapse procedure excluded because of nil group counts