Figure 4.
D614G and BA.1 pseudovirus neutralization with IgG and Fabs
(A) Representative BA.1-neutralizing antibodies were tested for neutralization of pseudovirus bearing D614G or BA.1 spike pseudovirus using whole IgG molecules or Fab fragments. Curves represent 3 biological replicates. The RBD-4b mAb (gray background) is a monovalent binder; all other IgGs shown here bind bivalently. Error bars are ± SEM.
(B) IC50 values for CoVIC antibodies and Fabs with D614G and BA.1 pseudoviruses.
See also Figure S3.