FIG. 3.

Dose response of 9HTEo− cytokine gene expression to increasing amounts of NTHi AAr176p⁺ whole cells. Epithelial cells were coincubated with 5 × 10⁵, 5 × 10⁶, 5 × 10⁷, and 5 × 10⁸ CFU of strain AAr176p⁺ per ml. Cytokine IL-6, IL-1α, IL-1β, TNF-α, IL-8, and MCP-1 expression is shown as fold increase over the unstimulated control. The data shown are from one representative experiment of four performed.