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. 2023 Jan 11;13:539. doi: 10.1038/s41598-023-27731-z

Table 2.

Median years of education and median difference in education (by quantile regression) comparing no hormone therapy use to systemic and local hormone therapy shown separately for each age group in the singleton population.

Median (IQR) Median difference (95% CI)
2000 2005 2000 2005
Age 51–55
No HT 13 (8–13) 0 (ref)
Systemic HT 13 (8–13) 0 (− 0.3; 0.3)
Local HT 13 (8–13) 0 (− 0.6; 0.6)
Age 56–60
No HT 11 (7–13) 13 (8–13) 0 (ref) 0 (ref)
Systemic HT 12 (7–13) 13 (8–13) 1.5 (0.8; 2.2) 0 (− 0.3; 0.3)
Local HT 12 (7–13) 13 (9–13) 1.5 (0.3; 2.7) 0 (− 0.3; 0.3)
Age 61–65
No HT 8 (7–13) 11 (7–13) 0 (ref) 0 (ref)
Systemic HT 11 (7–13) 12 (7–13) 3 (2.1; 3.9) 1 (0.3; 1.7)
Local HT 10 (7–13) 13 (7–13) 2 (0.7; 3.3) 2 (1.3; 2.7)
Age 66–70
No HT 7 (7–13) 9 (7–13) 0 (ref) 0 (ref)
Systemic HT 9 (7–13) 12 (7–13) 2 (1.5; 2.5) 3 (1.7; 4.3)
Local HT 10 (7–13) 10 (7–13) 3 (2.3 ; 3.7) 1 (− 0.1; 2.1)
Age 71–75
No HT 7 (7–13) 7 (7–13) 0 (ref) 0 (ref)
Systemic HT 9 (7–13) 9 (7–13) 2 (1.9; 2.1) 2 (1.3; 2.7)
Local HT 7 (7–13) 9 (7–13) 0 (− 0.1; 0.1) 2 (1.5; 2.5)
Age 76–80
No HT 7 (7–12) 7 (7–13) 0 (ref) 0 (ref)
Systemic HT 9 (7–13) 9 (7–13) 2 (1.9; 2.1) 2 (1.8; 2.2)
Local HT 7 (7–12) 7 (7–13) 0 (− 0.1; 0.1) 0 (− 0.1; 0.1)
Age 81–85
No HT 7 (7–13) 0 (ref)
Systemic HT 10 (7–13) 3 (2.9; 3.1)
Local HT 7 (7–13) 0 (− 0.1; 0.1)

HT, hormone therapy; IQR, interquartile range; CI, confidence interval.

Note. Due to data being restricted to include those with date of birth before January 1st 1950, there is no data for those aged 51–55 in 2005.