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. 2023 Jan 11;13:24. doi: 10.1038/s41598-022-22259-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Expression and genetic profiles of ARGs in SKCM. (a,b) Volcano and heat maps of DEGs in tumour and normal tissues. (c) Intersection of DEGs and ARGs. (d) Mutation frequency of differentially expressed ARGs. (e) Prediction of driver genes. (f) Synergy and mutual exclusivity of ARG mutations. DEG differentially expressed gene, ARG ageing-related gene.