Table 1.
Bivariate associations between proteins discovered in Kuan et al. (2020) and PTSD symptoms and diagnosis in the current sample.
| Kuan et al., 2020 | Total sample | ||||
|---|---|---|---|---|---|
| Significant proteins | Direction | PTSD symptoms (N = 936) | PTSD Diagnosis (N = 787) | ||
| r | p value | OR (95% CI) | p value | ||
| SKR3 | Up | 0.14 | 0.000 | 1.38 (1.14–1.68) | 0.001 |
| NCAN | Down | −0.12 | 0.001 | 0.80 (0.66-0.97) | 0.022 |
| BCAN | Down | −0.10 | 0.001 | 0.84 (0.68–1.02) | 0.075 |
| MSR1 | Up | 0.11 | 0.001 | 1.28 (1.04–1.58) | 0.018 |
| PVR | Up | 0.09 | 0.006 | 1.24 (1.02–1.52) | 0.035 |
| TNFRSF21 | Up | 0.10 | 0.002 | 1.27 (1.03–1.56) | 0.023 |
| DRAXIN | Up | 0.08 | 0.018 | 1.14 (0.94–1.38) | 0.193 |
| CTSS | Up | 0.05 | 0.139 | 1.12 (0.92–1.36) | 0.256 |
| MDGA1 | Up | 0.04 | 0.201 | 1.23 (1.01–1.51) | 0.041 |
| CPA2 | Up | 0.01 | 0.713 | 1.12 (0.91–1.36) | 0.283 |
| EDA2R | Up | 0.03 | 0.447 | 1.27 (1.00–1.62) | 0.052 |
| FLRT2 | Up | 0.04 | 0.237 | 1.30 (1.06–1.60) | 0.011 |
| ADAM22 | Down | −0.05 | 0.130 | 1.03 (0.84–1.26) | 0.775 |
| CTSC | Up | 0.00 | 0.915 | 1.12 (0.93–1.36) | 0.227 |
| CD200 | Up | 0.03 | 0.357 | 1.29 (1.06–1.58) | 0.013 |
| DDR1 | Up | 0.05 | 0.160 | 1.11 (0.91–1.35) | 0.325 |
| sFRP3 | Up | −0.01 | 0.666 | 1.06 (0.87–1.29) | 0.537 |
| VWC2 | Up | 0.05 | 0.125 | 1.28 (1.04–1.58) | 0.022 |
Replicated results after 5% FDR correction are bolded. Associations were adjusted for age and the time lag between PTSD assessment and blood draw.