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. 2023 Jan 11;8:3. doi: 10.1038/s41536-023-00276-5

Fig. 6. PDGF BB inhibits BMP2-induced osteogenesis in critical femoral defects.

Fig. 6

a Representative 3D images of μCT morphometry of healing defect 9 WPD with bone bridging. b Evaluation of bone volume within the defect with highest bone volume in group treated with 5 µg BMP2. c Histological evaluation of Col2.3GFP+ cells within defect area 9 WPD surgery. Scale bar of defect images is 1 mm. Saline control n = 2, n = 3–10 mice per experimental group. All the results are expressed as mean ± s.e.m. *p < 0.05, **p < 0.01, ***p < 0.001. Statistical test: One-way ANOVA with Tukey’s post hoc test.