Figure 1.

Malaria-associated cardiac injury and effect of GIE on parasitemia. (A) Monitoring parasitemia percentage and CPK level during 10 days post-infection. (B) Positive correlation between parasitemia and CPK level. (C) GIE treatment reduced the parasitemia percentage in 4-day PbANKA-infected mice. Results were expressed as mean + SEM. H: healthy; UN: untreated; GI100, GI250, and GI500: GIE treatment of 100, 250 and 500 mg/kg body weight of mice, respectively; CQ: CQ treatment of 10 mg/kg body weight of mice.

^#p < 0.05, ^##p < 0.01 and ^###p < 0.001, compared with UN.