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. 2022 Dec 24;8(12):e12570. doi: 10.1016/j.heliyon.2022.e12570

Table 1.

Patient demographic information. NAC: neoadjuvant chemotherapy, GemCis; gemcitabine plus cisplatin, NED: no evidence of disease, MVAC: methotrexate, vinblastine, doxorubicin, and cisplatin, 5-FU: fluorouracil, MMC: mitomycin C, NA: Not applicable, Pre Chemo: pre chemotherapy in locally advanced or metastatic setting, XRT: radiation therapy, Pembro: pembrolizumab, Fresh: tumor specimen engrafted directly from operating room, Cryo: tumor specimen engrafted from cryopreserved specimen, Minced: tumor specimen was engrafted as finely minced homogenate, Fragment: tumor specimen was engrafted as 2–3 mm fragment.

Sample ID Gender Age Ethnicity Histology Therapy Agent Pre or Post NAC Disease Status Experiment
BGB987445 Male 80 Not Hispanic or Latino Urothelial GemCIS Pre NAC Dead from disease PDX Growth Optimization (Fresh-Minced)
BGB420711 Male 72 Not Hispanic or Latino Urothelial MVAC Pre NAC Alive NED PDX Growth Optimization (Fresh-Minced)
BGB649851 Male 71 Not Hispanic or Latino Urothelial No NAC NA Alive NED PDX Growth Optimization (Fresh-Minced)
BGB247270 Male 83 Not Hispanic or Latino Urothelial w/85% Squamous 5-FU/MMC Pre Chemo/XRT Alive with disease PDX Growth Optimization (Fresh-Fragment)
BGB676371 Male 62 Hispanic or Latino Urothelial MVAC Pre NAC Alive NED PDX Growth Optimization (Fresh-Fragment)
BGB691147 Female 59 Not Hispanic or Latino Squamous Unknown Pre Chemo Alive with disease PDX Growth Optimization (Fresh-Fragment)
BGB687812 Male 78 Not Hispanic or Latino Urothelial No NAC NA Alive, disease status unknown PDX Growth Optimization (Cryo-Fragment)
BGB864465 Male 48 Not Hispanic or Latino Urothelial GemCIS Pre NAC Alive NED PDX Growth Optimization (Cryo-Fragment)
BGB248720 Male 79 Not Hispanic or Latino Urothelial No NAC NA Alive NED PDX Growth Optimization (Cryo-Fragment)
BGB331255 Male 77 Hispanic or Latino Urothelial GemCIS Pre NAC Alive NED PDX Growth Optimization (Cryo, Fresh-Fragment)
BGB490421 Male 92 Not Hispanic or Latino Urothelial Capecitabine Post NAC Alive with disease Chemotherapy Test
BGB450466 Female 70 Not Hispanic or Latino Urothelial GemCIS Pre NAC Dead from disease Chemotherapy Test
BGB680543 Male 61 Black or African American Urothelial GemCIS + Celecoxib + Pembro Pre NAC Alive NED Chemotherapy Test
BGB448649 Male 72 Not Hispanic or Latino Urothelial Gemcitabine Pre NAC Alive with disease Chemotherapy Test
BGB450544 Male 63 Not Hispanic or Latino Urothelial GemCIS Pre NAC Alive with disease Chemotherapy Test
BGB510249 Female 67 Not Hispanic or Latino Urothelial GemCIS Pre NAC Dead from disease Chemotherapy Test
BGB450466 Female 70 Not Hispanic or Latino Urothelial GemCIS Post NAC Dead from disease Kinase Inhibitor
BGB352747 Male 82 Not Hispanic or Latino Urothelial GemCIS Post NAC Dead from disease Kinase Inhibitor
BGB644697 Male 61 Not Hispanic or Latino Urothelial GemCIS Pre NAC Alive NED Kinase Inhibitor
BGB581979 Male 72 Not Hispanic or Latino Urothelial Gemcitabine + Cisplatin + Pembro Post NAC Deceased with unknown cause Kinase Inhibitor
BGB540726 Male 56 Not Hispanic or Latino Urothelial GemCIS Post NAC Dead from disease Kinase Inhibitor
BGB352747 Male 82 Not Hispanic or Latino Urothelial GemCIS Post NAC Dead from disease Kinase Inhibitor