TABLE 1.
Clinical decision support algorithms generated by NeoTree (other than resuscitation guidelines) according to degree of complexity (simple vs complex) and level of underlying evidence (strong vs weak)
| Data source | Category |
|---|---|
| 1. Simple conditional based decision trees based on based on strong evidence | |
| Birth weight measured/recorded on admission | Low birth weight |
| Very low birth weight | |
| Extremely low birth weight | |
| Appropriate for gestational age | |
| High birth weight | |
| Gestational age recorded on admission | Premature |
| Very premature | |
| Extremely premature | |
| Term | |
| Post‐dates | |
| Maternal HIV status recorded on admission | HIV exposed (high risk) |
| HIV exposed (low risk) | |
| Maternal Syphilis status recorded on admission | Untreated maternal syphilis |
| Temperature recorded on admission | Normothermia |
| Mild hypothermia | |
| Moderate hypothermia | |
| Severe hypothermia | |
| Blood sugar on admission | Hypoglycaemia |
| Risk of hypoglycaemia | |
| Abnormal findings on clinical examination | Clinical jaundice |
| Clinical convulsions | |
| Dehydration | |
| Ambiguous genitalia | |
| Congenital abnormality | |
| Clinical examination/maternal history | Consider tetanus |
| 2. Simple conditional expressions based on weak evidence | |
| Abnormal findings on clinical examination/maternal history | Difficulty feeding |
| Birth trauma | |
| Consider abdominal obstruction | |
| Consider congenital heart disease (CHD) | |
| Consider anaemia | |
| 3. Complex conditional expressions based on strong evidence | |
| Clinical examination ‐ Thompson score | Neonatal encephalopathy |
| Clinical examination ‐ triggers/risk factors | Consider Neonatal encephalopathy |
| Clinical examination/history | Respiratory distress of the newborn a |
| 4. Complex conditional expression based on weak evidence (in low resource settings) | |
| Clinical examination and history (but not investigations) | Risk factors for early onset neonatal sepsis |
| Risk factors for late onset neonatal sepsis | |
| Early onset neonatal sepsis | |
| Late onset neonatal sepsis | |
| Consider Necrotising Entero‐Colitis (NEC) | |
| Consider meningitis | |
a
RDS categories to be developed: Possible meconium aspiration; respiratory distress of prematurity; transient tachypnoea of the newborn; congenital pneumonia; pneumonia/bronchiolitis.