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. Author manuscript; available in PMC: 2023 Jan 16.
Published in final edited form as: Mucosal Immunol. 2022 Jul 16;15(5):1000–1011. doi: 10.1038/s41385-022-00544-5

Figure 5: Altered alpha and beta diversity in mice that had an antibiotic-perturbed or control microbiota from birth.

Figure 5:

A. Alpha diversity across P25, P40 and P60 for each group of mice based on birth-microbiota. Significance for alpha diversity was determined by a nonparametric one-way ANOVA (*p<0.05; **p<0.01; ***p<0.001) B. Beta diversity, based on unweighted UniFrac analysis of P25, P40, P65 fecal pellets. Each sample is color-coded by microbiota group and symbols are used to differentiate day of life. Permutational Multivariate Analysis of Variance was performed to compare microbiota, day of life, and the interaction of both factors (p-value < 0.001); 41% of variance could be attributed to the founding microbiota source; 3.5% of variance could be attributed to day of life, and 3.3% of variance was attributed to both microbiota source and day of life.