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. Author manuscript; available in PMC: 2023 Jan 12.
Published in final edited form as: Stat Sin. 2022;32:1983–2005. doi: 10.5705/ss.202020.0248

Table 5:

Toxicity scenarios 1–4 for the two-drug combinations. Dose combinations in the minimal set are in bold. Doses associated to a toxicity probability equal to 0.20 belong to D and D+ (see Section 4); they are always in the minimal set.

Dose Drug A2
Level 1 2 3 4 1 2 3 4
Scenario 1 Scenario 2
4 22 26 30 34 55 65 75 85
3 16 20 24 28 40 50 60 70
2 10 14 18 22 25 35 45 55
1 4 8 12 16 10 20 30 40
Drug
A1 Scenario 3 Scenario 4
4 11 21 31 41 10 30 50 80
3 10 20 30 31 6 15 30 45
2 9 19 29 30 4 10 15 20
1 8 18 28 29 1 2 3 4