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. Author manuscript; available in PMC: 2023 Jan 12.
Published in final edited form as: Stat Sin. 2022;32:1983–2005. doi: 10.5705/ss.202020.0248

Table 7:

True toxicity probabilities for the four scenarios of a 6 × 6 grid, with maximum tolerated doses shown in bold

Dose Drug A1
Level 1 2 3 4 5 6 1 2 3 4 5 6
Scenario 1 Scenario 2
6 20 29 31 43 47 50 37 45 51 54 55 58
5 18 20 29 34 41 48 30 38 41 43 46 47
4 16 19 21 32 36 42 23 25 35 36 40 42
3 10 15 20 25 30 37 19 20 26 33 35 39
2 3 9 16 19 21 32 15 17 21 24 31 33
1 2 5 10 17 21 30 5 10 16 20 25 28
Drug
A2 Scenario 3 Scenario 4
6 11 13 15 17 25 33 65 70 76 80 84 90
5 9 11 13 15 16 25 55 63 69 77 80 85
4 7 9 11 14 15 17 45 56 60 72 76 79
3 5 8 10 11 13 15 35 42 52 65 70 73
2 3 6 7 9 12 13 25 34 46 54 60 64
1 1 3 5 7 9 11 15 25 36 43 49 55