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. 2022 Dec 28;8(1):1–9. doi: 10.1021/acsomega.2c06034

Table 1. Biomedical Applications of Archaeosomes-Based Formulations.

Drug/biomolecule Application Mechanism of action Inferences Refs
Doxorubicin (DOX) drug Cancer therapy Hyperthermia-induced cell death Sustained drug release and reduced side effects (3)
Plasmid DNA Gene delivery Transfection Cations help to improve the transfection process (7)
BMD drug Anti-inflammatory Absorption to the deeper layers Effective drug penetration and accumulation in the epidermis (11)
A1 peptide Cancer therapy Cause rapid leakage of cytoplasmic contents Cytotoxic to cancer cells (12)
PTX drug Cancer therapy Enhance polymerization of tubulin Reduce side effects and improve its therapeutic index (14)
Phenol (recovered from olive mill waste) Antioxidant Inhibit cell damage High stability, sustained drug release (21)
Insulin Diabetes treatment Reduce blood glucose levels Stable in simulated gastrointestinal tract conditions, poor permeability of the intestinal epithelium (22)
BSA Vaccine therapy Stimulated proliferation of CD8+ T cells Modulate primary, long-term, and/or innate immunity, impacting adjuvant choice for vaccine design (26)
BSA/cholera toxin B subunits Vaccine delivery Increased antibody production Better humoral immune response (28)