Figure 1. Comparison of gene expression profiles between the PPS and NPPS groups.
(A) The PCA shows the global gene expression level distinctions between the PPS and NPPS groups. The red circle represents samples from the PPS group, and the blue triangle represents samples from the NPPS group. (B) Venn diagram shows that 9,257 genes are overlapped by two groups, while 3,910 genes are unique to the PPS group and 174 genes are unique to the NPPS group. (C) The volcano plot shows the distribution of differentially expressed genes. The red dots represent the genes significantly up-regulated, while the blue dots represent the genes significantly down-regulated. The gray dots represent the genes with no significant differences between groups. (D) Heat map analysis shows the upregulated or down-regulated gene clusters originated from different samples.