Figure 1: Host response-based screen for undiagnosed infections (week 4, January, 2017).
(A) The screening process for samples tested with the respiratory virus panel. True unknowns were negative for the ten viruses on the respiratory virus panel and parainfluenza virus 4 and four seasonal coronaviruses (not included in the respiratory virus panel). (B) Nasopharyngeal CXCL10 concentrations for virus PCR-negative samples, showing those selected for RNA sequencing (samples A–H) based on CXCL10 (>1 ng/mL) and sufficient RNA content. (C) Reads in sample A map to each of the seven gene segments of the influenza C virus genome.