TABLE 1.
Effects of SEB and LPS on cytokine production
| Treatmenta | Cytokine production (pg/ml)b
|
|||
|---|---|---|---|---|
| IL-4 | IL-1β | IL-10 | TNF-α | |
| None | <10 | <20 | <20 | <20 |
| LPS | <10 | 1,013 ± 28 | 549 ± 55 | 1,534 ± 74 |
| SEB | 16 ± 1 | 49 ± 2 | 171 ± 11 | 132 ± 4 |
a
PBMC (106/ml) were cultured with SEB (1 μg/ml) or LPS (1 μg/ml) for defined periods.
b
IL-4 (18 h), IL-1β (6 h), IL-10 (9 h), and TNF-α (6 h) contents of the supernatants were determined by ELISA. All samples were assayed in triplicate, and the results are expressed as means ± SD.