TABLE 4.
Patients | Summary statistics | |
MCIDs reached | ||
MCID LCQ +1.3 reached | 806 | |
No | 287 (35.6) | |
Yes | 519 (64.4) | |
MCID NRS-cough −2.0 reached | 1734 | |
No | 854 (49.3) | |
Yes | 880 (50.7) | |
MCID LCQ and/or NRS-cough reached | 712# | |
LCQ not reached and NRS-cough not reached | 192 (27.0) | |
LCQ reached and NRS-cough not reached | 146 (20.5) | |
LCQ not reached and NRS-cough reached | 68 (9.6) | |
LCQ reached and NRS-cough reached | 306 (43.0) | |
Any MCID reached | 712# | |
No | 192 (27.0) | |
Yes | 520 (73.0) | |
Residual burden of cough | ||
LCQ <13 and/or NRS-cough >5 | 909 | |
No | 554 (60.9) | |
Yes | 355 (39.1) | |
Effectiveness of treatment | ||
Treatment effectiveness | 712# | |
No MCID and R-cough | 126 (17.7) | |
No MCID and no R-cough | 66 (9.3) | |
Any MCID and R-cough | 144 (20.2) | |
Any MCID and no R-cough | 376 (52.8) | |
Treatment effectiveness | 712# | |
Not effective | 336 (47.2) | |
Effective | 376 (52.8) |
Data are presented as n or n (%). MCID: minimal clinically important difference; LCQ: Leicester Cough Questionnaire; NRS-cough: Cough Numeric Rating Scale; R-cough: remaining cough. #: all patients included in the trial, regardless of available diagnosis data.