Table 4. Results of each model on the independent test set using four metrics.

Methods	ACC (%)	MCC	SN (%)	SP (%)
SMFM	82	0.651	83.25	81.5
iEnhancer-2L	73	0.460	71	75
EnhancerPred	74	0.480	73.5	74.5
iEnhancer-EL	74.75	0.496	71	78.5
iEnhancer-XG	75.75	0.515	74	77.5
BERT-2DCNNs	75.6	0.514	80	71.2
iEnhancer-EBLSTM	77.2	0.534	75.5	79.5
iEnhancer-ECNN	76.9	0.537	78.5	75.2
Enhancer-IF	79.3	0.585	80.5	78.7