Figure 5: Decellularized ECM imaged with two-photon microscopy.

(A) SHG images of collagen fibers from a 6 μm liver slice (fresh frozen) without decellularization. (B) SHG images depict a well-organized collagen network in livers of mice on normal control, chow diet. Remodeled collagen network in mice on fast-food diet (FFD). Arrow, fibrosis area. Star, remodeled collagen network. Scale bar = 100 μm.