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. 2023 Jan 12;13:643. doi: 10.1038/s41598-022-27149-z

Table 1.

Characteristics and properties of approved cholinesterase inhibitors.

Compound and PubChem CID Mechanism of inhibition Penetration through blood–brain barrier 2D structure

Rivastigmine

77991

Non-competitive Good graphic file with name 41598_2022_27149_Figa_HTML.gif

Tacrine

1935

Non-competitive Good graphic file with name 41598_2022_27149_Figb_HTML.gif

Galantamine

9651

Competitive Good graphic file with name 41598_2022_27149_Figc_HTML.gif

Donepezil

3152

Non-competitive Good graphic file with name 41598_2022_27149_Figd_HTML.gif

Huperzine

1253

Non-competitive Good graphic file with name 41598_2022_27149_Fige_HTML.gif