Table 4.

Patient characteristics and pMMA and uMMA values of a subset of individuals from the MARLINA trial. Number of individuals with low, medium and high pMMA and uMMA levels grouped by Race and Sex.

	Group	Race	Sex	n	pMMA nmol/L			uMMA µmol/mmol Creatinine
					Low < 50	Medium 50–270	High ≥ 270	Low < 0.4	Medium 0.4–3.5	High ≥ 3.5
1	Placebo	Asian	Female	36	0	14	22	2	20	14
2		Asian	Male	59	0	31	28	5	41	13
3		Other/unknown	Male	1	0	1	0	1	0	0
4		Unknown	NA	25	0	13	12
5		White	Female	7	0	7	0	3	3	1
6		White	Male	22	2	14	6	5	13	4
7	Linagliptin 5 mg	Asian	Female	34	0	18	16	2	23	9
8		Asian	Male	54	0	20	34	5	38	11
9		Other/unknown	Female	1	0	0	1	0	1	0
10		Unknown	NA	31	0	17	14
11		White	Female	11	0	9	2	1	8	2
12		White	Male	20	0	16	4	3	16	1

NA not applicable; pMMA plasma methylmalonic acid; uMMA urine methylmalonic acid.