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. 2022 May 17;140(19):2053–2062. doi: 10.1182/blood.2022015403

Table 3.

Absolute hemoglobin levels (g/dL) in response to mitapivat treatment

Measurement N Mean SD 25th percentile Median 75th percentile
Baseline 16 9.19 1.10 8.55 9.55 9.93
5 mg BID 16 9.53 1.22 8.43 9.80 10.43
20 mg BID 16 9.95 1.28 9.00 10.00 10.83
50 mg BID 16 10.38 1.21 9.52 10.15 11.25
100 mg BID 9 10.06 1.00 9.30 10.30 10.80
End of taper 15 9.43 1.24 8.70 9.60 10.40
End of study 15 9.64 1.33 8.65 9.60 10.60