Table 4.

Change in hemoglobin levels (g/dL) in response to mitapivat treatment

Measurement	N	Mean	SD	25th percentile	Median	75th percentile
Baseline	16	0.00	0.00	0.00	0.0	0.00
5 mg BID	16	0.34	0.70	−0.12	0.3	0.80
20 mg BID	16	0.76	0.96	−0.10	0.7	1.30
50 mg BID	16	1.19	0.95	0.57	1.1	1.65
100 mg BID	9	0.87	1.12	0.40	0.8	0.90
End of taper	15	0.29	0.82	−0.20	0.3	0.55
End of study	15	0.40	0.69	0.05	0.6	0.90