Table 1.
ASD | NT | ||||
---|---|---|---|---|---|
Females | Males | Females | Males | Difference? | |
n | 24 | 21 | 21 | 19 | |
Age | 39.42 (13.21) 19–60 | 41.95 (11.39) 26–64 | 43.57 (15.68) 18–65 | 48.53 (13.35) 26–70 | None |
CAT-Q | 120.21 (30.34) 49–164 | 107.00 (23.29) 64–161 | 63.95 (24.45) 38–139 | 72.68 (13.34) 55–101 | aASD > NT, aASD-F > ASD-M |
IQ | 110.25 (16.94) 73–148 | 104.14 (15.95) 70–131 | 108.05 (12.71) 77–132 | 107 (11.24) 92–127 | None |
SRS-2 | 103.87 (29.56) 44–167 | 110.43 (35.45) 21–155 | 21.95 (9.67) 5–46 | 26.95 (14.45) 7–57 | b ASD>NT |
ADOS-2 | 9.87 (2.13) 7–14 | 10.67 (3.73) 7–19 | N/A | N/A | None |
rs-fMRI Motiond | 0.06 (0.02) 0.02–0.08 | 0.07 (0.02) 0.02–0.11 | 0.06 (0.01) 0.04–0.09 | 0.07 (0.03) 0.02–0.13 | None |
DTI Motionc d | 0.34 (0.13) 0.16–0.61 | 0.65 (0.61) 0.19–3.01 | 0.31 (0.15) 0.12–0.64 | 0.60 (0.38) 0.30–1.63 | e male>female |
Education (years) | 16.08 (2.32) 12–20 | 15.29 (2.90) 12–22 | 16.67 (2.22) 12–21 | 16.79 (2.15) 14–23 | f ASD<NT |
Differences were tested via ANOVA for main effects of diagnosis, sex, or their interaction. If significant, post-hoc t-tests examined pairwise group differences driving the significant main effect or interaction. *Social Responsiveness Scale—2nd Edition (SRS-2); at83 = 8.62, P < 0.001;
a t 43 = 1.62, P = 0.11,
b t 83 = 15.25, P < 0.001;
caverage root mean square displacements relative first volume;
dno group differences in percent outlier slices or framewise displacement;
e t 83 = 3.79, P < 0.001,
f F 1,81 = 3.93, P = 0.051.
gCONN average motion observed (disregarding outlier scans; threshold = 0.5).