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. 2022 Dec 23;15(1):416–431. doi: 10.1021/acsami.2c17424

Figure 7.

Figure 7

Fe-TA@P(AM-AA) promotes the wound healing of oral mucosa in the diabetic rat model. (A) Diabetic rat oral mucosa defects (1.2 mm diameter) were created above the muscle tissue and covered with Fe-TA@P(AM-AA) (10 wt %). Untreated oral mucosal defects were taken as the control group. (B) Wound-healing areas of rat oral mucosa were calculated on days 1, 3, 5, and 7 after treatment. (C) H&E staining showing the epithelial healing of the diabetic rat palatal mucosa defects at different time points. The thickness of the repaired epithelium was measured to evaluate the effect of the composite gel. (D) CD31-stained blood vessels in the defect regions. (E) Ki67-stained proliferative cells in the defect regions.