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Excised rs356182 by CRISPR-Cas9. (A) Schematic depicting the position of rs356182 relative to SNCA on chromosome 4 and the guide-RNA targeting that locus for a double stranded DNA break. (B) The resulting deletions (deleted bases depicted as dashes) from targeting rs356182 with CRISPR-Cas9; position of rs356182 highlighted in red.
