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. 2022 Oct 11;18(6):1354–1363. doi: 10.4103/1673-5374.357911

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Copyright: © Neural Regeneration Research

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Protein network data of compa2 by STRING database (Rattus norvegicus).

Analysis of protein-protein interactions of 92 significantly different proteins in compa2 (SNC vs. WT). Nodes represent a single protein-coding gene locus. Splice isoforms or post-translational modifications are collapsed, thus 85 nodes appear. Edges represent protein-protein associations meaning that proteins jointly contribute to a shared function. Average local Markov clustering coefficient = 0.453. Dotted lines represent edges between clusters. The thickness of the edge line is proportional to the edge confidence. Each color represents a cluster of proteins. There are 22 clusters based on enrichment pathways. compa2: Comparison between SNC and the WT rats 5 weeks after injury. SNC: Sciatic nerve crush; WT: wild-type.