Table 2.
Comparison of clinical parameters between groups at baseline and day 90
| Variable | Timepoint | Hand instrumentation n = 19 |
Ultrasonic instrumentation n = 18 |
Combination instrumentation n = 18 |
Between group p value* |
|---|---|---|---|---|---|
| PISA (mm2) | Baseline | 1,010.02 (561.99, 2,190.01) | 957.93 (385.55, 1,759.57) | 1,277.45 (730.13, 1,837.63) | 0.856 |
| Day 90 | 192.59 (59.78, 380.49) | 134.85 (62.31, 219.72) | 124.20 (58.80, 358.10) | ||
| Change | ↓ 936.10 (304.36, 1,392.59) | ↓ 743.57 (268.76, 1,589.81) | ↓ 1,167.35 (674.53, 1,743.58) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
| PPD (mm) | Baseline | 3.98 (3.11, 4.78) | 3.70 (3.35, 4.12) | 3.74 (3.04, 4.37) | 0.394 |
| Day 90 | 3.02 (2.52, 3.73) | 2.68 (2.39, 3.09) | 2.77 (2.48, 3.24) | ||
| Change | ↓ 0.87 (0.51, 1.38) | ↓ 1.0 (0.79, 1.31) | ↓ 0.95 (0.46, 1.36) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
| Pockets ≥5 mm (%) | Baseline | 28.85 (18.33, 51.39) | 26.73 (22.08, 36.71) | 29.5 (17.75, 48) | 0.636 |
| Day 90 | 11.67 (3.89, 30.95) | 10.88 (3.87, 16.88) | 10.00 (3.50, 12.25) | ||
| Change | ↓ 17.30 (11.29, 23.21) | ↓ 16.87 (12.83, 25.69) | ↓ 16.5 (12.0, 34.75) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
| Full mouth BOP (%) | Baseline | 45.0 (21.26, 69.44) | 38.11 (21.45, 61.49) | 66 (32.25, 81.75) | 0.715 |
| Day 90 | 8.33 (2.98, 13.10) | 8.10 (4.12, 12.08) | 8.5 (3.75, 18.00) | ||
| Change | ↓ 35.00 (10.92, 52.23) | ↓ 28.37 (16.17, 49.32) | ↓ 50.5 (28.0, 69.5) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
| Full mouth plaque (%) | Baseline | 60.48 (25.0, 67.74) | 45.92 (26.1, 63.33) | 62.5 (45.5, 78.75) | 0.595 |
| Day 90 | 8.33 (4.17, 14.06) | 7.80 (3.50, 13.25) | 13.00 (7.75, 28.5) | ||
| Change | ↓ 44.35 (18.10, 51.66) | ↓ 33.23 (15.21, 48.67) | ↓ 42.0 (27.75, 56.75) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
| CAL (mm) | Baseline | 4.36 (3.29, 5.02) | 4.14 (3.66, 4.43) | 4.51 (3.8, 5.38) | 0.194 |
| Day 90 | 4.01 (3.03, 4.68) | 3.63 (3.10, 4.12) | 3.42 (2.81, 4.14) | ||
| Change | ↓ 0.36 (0.05, 1.12) | ↓ 0.52 (0.26, 0.80) | ↓ 1.03 (0.72, 1.51) | ||
|
Within group p-value** |
<0.001 | <0.001 | <0.001 | ||
|
Key: * = non-parametric variables were ln-transformed, then general linear modelling was used to test differences in clinical parameters between the groups at day 90, adjusting for base-line levels of clinical variable, smoking status, treatment time, age, sex and number of teeth. ** = differences in median values between baseline and day 90 within groups tested using Wilcoxon signed rank test. Clinical measures of periodontitis disease state for baseline and day 90 following treat-ment. Patients are grouped according to treatment received. Values are presented as median (Q1, Q3). Magnitude of improvement in clinical measures of periodontitis disease state following treatment are shown in the 'change' row. All data are presented as median (Q1, Q3) and are relative to baseline measurements, apart from pocket closure% (defined as percentage of pockets being converted from ≥5 mm probing depth to ≤4 mm probing depth following treatment). Arrows denote direction of change - calculated by subtracting pre-treatment value of varia-ble from post-treatment value. | |||||