TABLE 3.
Associations of Primary Short-Term and Long-Term Outcomes With Presence of Postnatal CMV Infection and Antiviral Treatment
| CMVPNT vs. NEG | CMVPT vs. NEG | ||||||
|---|---|---|---|---|---|---|---|
| NEG (n = 50) | CMVPNT (n = 26) | CMVPT (n = 27) | OR (95% CI) | P | OR (95% CI) | P | |
| Me (IQR) Length of stay [days] | 94 (69–112) | 85 (70–102) | 100 (88–137) | 0.99 (0.98–1.01) | 0.457 | 1.01 (1–1.02) | 0.103 |
| Death before discharge [n (%)] | 3 (6) | 1 (3.8) | 1 (3.7) | 0.63 (0.06–6.34) | 0.692 | 0.6 (0.06–6.09) | 0.668 |
| Hearing at follow-up | |||||||
| Normal hearing [n (%)] | 30 (81.1) | 13 (100) | 17 (85) | – | 0.032 a | 1.32 (0.3–5.79) | 0.711 |
| Sensorineural hearing loss [n (%)] | 7 (18.9) | 0 (0) | 3 (15) | ||||
| Denver developmental screening test II | |||||||
| Me (IQR) Gross motor domain score | 0.94 (0.8–1) | 0.98 (0.88–1) | 1 (0.96–1) | – | 0.635b | – | 0,115b |
| Me (IQR) Fine motor domain score | 1 (0.92–1) | 1.06 (0.98–1.23) | 1 (0.88–1) | – | 0.077b | – | 0.694b |
| Me (IQR) Speech domain score | 0.93 (0.83–1) | 1 (0.9–1) | 0.92 (0.88–1) | 2.89 (0.11–72.82) | 0.519 | 3.97 (0.2–79.6) | 0.368 |
| Me (IQR) Socialization domain score | 1 (1–1) | 1 (0.96–1) | 1 (0.85–1) | 0.77 (0.01–77.65) | 0.91 | 1.26 (0.02–104.03) | 0.918 |
| Neurologic status | |||||||
| Normal [n (%)] | 21 (56.8) | 9 (69.2) | 14 (70) | 1.71 (0.45–6.58) | 0.432 | 1.78 (0.56–5.65) | 0.33 |
| Abnormal [n (%)] | 16 (43.2) | 4 (30.8) | 6 (30) | ||||
CI, confidence interval; CMVPNT, CMV positive without antiviral treatment group; CMVPT, CMV positive on antiviral therapy group; IQR, interquartile range; Me, median; n, number of subjects; NEG, CMV negative group (control group); OR, odds ratio.
Odds ratio test.
Mann–Whitney U test.