Figure 4.

Synaptic decoupling between ChR⁺ and ChR^– pyramidal neurons. A, Example traces of a paired recording between reciprocally connected ChR^– and ChR^– pyramidal neurons (<50 μm apart). B, EPSP amplitude and slope were significantly reduced between connected pairs of ChR⁺ and ChR^– pyramidal neurons compared with connected pairs of ChR^– pyramidal neurons following 48 h of stimulation. C, Connectivity ratio was higher between pairs of ChR^– pyramidal neurons compared with pairs of ChR⁺ and ChR^– pyramidal neurons.