Skip to main content
. 2021 Nov 8;2(2):120–131. doi: 10.1021/acsmeasuresciau.1c00030

Figure 2.

Figure 2

Quantification of dyskinetic behavior. (a) After 1 week of L-DOPA administration (6 mg/kg), lesioned rats exhibited AIMs that differed from baseline (0 min). These peaked 60–100 min after drug administration (#P < 0.05, ##P < 0.01). After 3 weeks of L-DOPA, dyskinetic movements increased and were evident for a longer duration (40–100 min, ++++P < 0.0001). The total score for global AIMs increased from week 1 to week 3 after daily L-DOPA treatment (*P < 0.05). (b) The number of rotations (360°, per min) increased compared to baseline (0 min) in both week 1 (20–60 min, #P < 0.05, ##P < 0.01) and week 3 (20 and 40 min, +P < 0.05). For both weeks, n = 7.