Skip to main content
. 2023 Jan 13;18(1):e0280304. doi: 10.1371/journal.pone.0280304

Fig 3. Implanted HAP stem cells inhibit glial scar formation at the ICH site in C57BL/6J.

Fig 3

(A, B) Expression of GFAP of astrocytes in the ICH area with and without HAP-stem-cell-implantation in C57BL/6J mice. Glial scar formation was observed in the non-implanted control mice but not HAP-stem-cell-implanted mice. (C, D) Expression of Iba-1 of microglia in the ICH area with and without HAP-stem-cell implantation in C57BL/6J mice. (E) The GFAP-positive area in coronal section of the brain in C57BL/6J mice was smaller in the HAP-stem-cell-implanted mice than in the non-implanted control mice (n = 4, each group). *P < 0.05. (F) The Iba-1-positive area in coronal sections of the brain in C57BL/6J mice was smaller in the HAP-stem-cell-implanted mice than in the non-implanted control mice (n = 4, each group). *P < 0.05. Bar = 50 μm. All images show coronal sections of the brain.