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. Author manuscript; available in PMC: 2023 Jan 13.
Published in final edited form as: Cell Rep. 2022 Dec 20;41(12):111860. doi: 10.1016/j.celrep.2022.111860

Table 1.

Ex vivo cortico-claustral-cortical circuit mapping average area under the curve and number of action potentials per light pulse values

Outputs
Inputs Type I
ACC plPFC ilPFC OFC RSC V1/V2 PtA
ACC 980.57 ± 234.03 1,726.36 ± 500.26 874.5 ± 158.12 365.18 ± 97.84 543.90 ± 100.59 1,187.82 ± 339.33 2,612.2 ± 499.74
pIPFC 1,110.11 ± 329.41 829.25 ± 283.61 −126.12 ± 75.50 910.73 ± 253.03 −5.03 ± 37.58 2,063.42 ± 642.18 2,857.86 ± 1,006.19
ilPFC 90.03 ± 10.76 −87.94 ± 34.25 418.33 ± 82.48 921.15 ± 214.65 948.56 ± 203.32 585.93 ± 95.61 425.83 ± 69.29
OFC 558.56 ± 120.27 391.55 ± 72.17 437.82 ± 79.15 334.97 ± 56.41 260.83 ± 40.83 514.24 ± 135.05 318.96 ± 51.90
aINS 133.14 ± 24.28 126.87 ± 25.88 361.20 ± 66.63 170.44 ± 20.30 259.51 ± 46.23 97.69 ± 21.15 261.55 ± 54.64
Type II
ACC plPFC ilPFC OFC RSC V1/V2 PtA
ACC 1,888.64 ± 621.51 2,283.24 ± 718.96 1,630.08 ± 437.59 1,092.71 ± 369.70 1,018.83 ± 228.81 1,387.44 ± 427.60 1,846.68 ± 611.11
pIPFC 1,448.17 ± 422.10 1,397.84 ± 400.05 257.79 ± 33.61 711.19 ± 171.64 904.83 ± 172.07 2,963.15 ± 972.68 2,698.31 ± 997.09
ilPFC 393.51 ± 55.72 367.92 ± 66.75 1,521.39 ± 379.03 646.72 ± 141.09 3,024.88 ± 900.08 974.24 ± 205.79 1,208.80 ± 261.53
OFC 645.47 ± 158.26 496.05 ± 103.38 590.06 ± 118.20 576.29 ± 143.41 1,006.56 ± 288.62 634.90 ± 218.70 495.16 ± 158.10
aINS 137.10 ± 14.48 114.51 ± 23.34 196.16 ± 21.01 222.86 ± 21.19 257.16 ± 44.34 150.73 ± 18.56 273.46 ± 93.64
Outputs
Inputs Type I
ACC plPFC ilPFC OFC RSC V1/V2 PtA
ACC 0.20 ± 0.09 0.11 ± 0.06 0.03 ± 0.01 0.00 ± 0.00 0.11 ± 0.05 0.14 ± 0.08 0.19 ± 0.10
pIPFC 0.11 ± 0.07 0.10 ± 0.05 0.00 ± 0.00 0.04 ± 0.02 0.00 ± 0.00 0.36 ± 0.12 0.40 ± 0.15
ilPFC 0.00 ± 0.00 0.00 ± 0.00 0.06 ± 0.03 0.02 ± 0.01 0.10 ± 0.04 0.01 ± 0.01 0.01 ± 0.01
OFC 0.05 ± 0.03 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.01 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
aINS 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
Type II
ACC plPFC ilPFC OFC RSC V1/V2 PtA
ACC 0.55 ± 0.21 0.55 ± 0.23 0.52 ± 0.18 0.14 ± 0.09 0.13 ± 0.07 0.46 ± 0.18 0.48 ± 0.22
pIPFC 0.26 ± 0.12 0.30 ± 0.14 0.00 ± 0.00 0.05 ± 0.03 0.02 ± 0.01 1.04 ± 0.36 0.70 ± 0.26
ilPFC 0.00 ± 0.00 0.01 ± 0.00 0.32 ± 0.11 0.09 ± 0.03 0.78 ± 0.38 0.07 ± 0.03 0.09 ± 0.04
OFC 0.01 ± 0.01 0.00 ± 0.00 0.00 ± 0.00 0.02 ± 0.01 0.11 ± 0.06 0.01 ± 0.01 0.02 ± 0.01
aINS 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00

Top: average area under the curve values across all light intensities tested (0, 0.6, 1.2, 1.8, 2.4, and 3 mW) for all type I and II claustrum neurons tested (n = 1,050 cells). Bottom: average number of action potentials per light pulse values across all light intensities. Error shown is standard error of the mean. Average area under the curve units = mV × ms.