Table 3.
Comparison characteristics between groups according to the scale of AchR Ab titer.
| Parameters | AchR Ab titer < 5.0 (n = 9) | AchR Ab titer > 5.0 (n = 9) | P value |
|---|---|---|---|
| Age at time of onset (yrs) | 57.0 ± 14.30 | 51.40 ± 12.38 | .658 |
| Male: Female (n) | 4: 5 | 4: 5 | >.999 |
| Ptosis grade (1:2:3) (11) (n) | 2: 1: 1 | 0: 5: 2 | .179 |
| Ocular symptoms (n) | |||
| Ptosis | 1 (11.11%) | 2 (22.22%) | >.999 |
| Diplopia | 5 (55.56%) | 2 (22.22%) | .437 |
| Ptosis & Diplopia | 3 (33.33%) | 5 (55.56%) | .637 |
| Horizontal or vertical diplopia (15) (n) | 7 (62.50%) | 2 (100.0%) | .200 |
| Horizontal & vertical diplopia (15) (n) | 1 (12.50%) | 5 (71.43%) | .041 |
| Angle of horizontal diplopia (12) (PD) | 18.60 ± 10.90 | 11.86 ± 6.09 | .320 |
| Angle of vertical diplopia (9) (PD) | 4.00 ± 2.31 | 11.40 ± 10.71 | .123 |
| AchR Ab titer (nmol/L) | 2.02 ± 1.54 | 10.0 ± 1.99 | <.001 |
| Abnormal RNST (n) | 4 (44.44%) | 4 (44.44%) | >.999 |
| Abnormal thymic lesion (n) | 1 (11.11%) | 6 (66.67%) | .050 |
| Thyroid disease (n) | 2 (22.22%) | 2 (22.22%) | >.999 |
| Secondary GMG (n) | 1 (11.11%) | 3 (33.33%) | .576 |
| Treatment to steroid (n) | 5 (55.56%) | 8 (88.89%) | .294 |
| Side effects of treatment (n) | 3 (33.33%) | 1 (11.11%) | .576 |
Values are presented as mean ± SD.
AchR Ab = acetylcholine receptor auto-antibodies, GMG = generalized myasthenia gravis, PD = prism diopters, RNST = repetitive nerve stimulation test, SD = standard deviation.