Table 4.
Comparison characteristics of ocular symptoms (ptosis and diplopia vs ptosis or diplopia).
| Parameters | Ptosis and Diplopia (n = 8) | Ptosis or Diplopia (ptosis = 14; diplopia = 6) | P value |
|---|---|---|---|
| Age at time of onset (yrs) | 51.75 ± 18.68 | 56.85 ± 12.72 | .558 |
| Male: Female (n) | 2: 6 | 10: 10 | .401 |
| Ptosis grade (1:2:3) (n) | 1: 5: 2 | 1: 3: 2 | >.999 |
| Horizontal & vertical diplopia (n) | 6 (75.0%) | 1 (7.14%) | .002 |
| Angle of horizontal diplopia (17) (PD) | 12.67 ± 5.43 | 12.09 ± 10.05 | .609 |
| Angle of vertical diplopia (12) (PD) | 8.88 ± 8.90 | 4.50 ± 3.00 | .375 |
| Seropositive AchR Ab (n) | 7 (87.50%) | 9 (45.0%) | .088 |
| AchR Ab titer (7 vs 9) (nmol/L) | 7.61 ± 3.29 | 5.64 ± 5.20 | .427 |
| Abnormal RNST (n) | 4 (50.0%) | 4 (20.0%) | .172 |
| Abnormal thymic lesion (n) | 3 (37.50%) | 4 (20.0%) | .371 |
| Thyroid disease (n) | 3 (37.50%) | 3 (15.0%) | .311 |
| Secondary GMG (n) | 4 (50.0%) | 0 (0.00%) | .003 |
| Treatment to steroid (n) | 8 (100.0%) | 10 (50.0%) | .025 |
| Side effects of treatment (n) | 2 (25.0%) | 3 (15.0%) | .606 |
Values are presented as mean ± SD.
AchR Ab = acetylcholine receptor auto-antibodies, GMG = generalized myasthenia gravis, PD = prism diopters, RNST = repetitive nerve stimulation test, SD = standard deviation.