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. Author manuscript; available in PMC: 2023 Apr 3.
Published in final edited form as: Nat Methods. 2022 Oct 3;19(10):1234–1242. doi: 10.1038/s41592-022-01605-0

Extended Data Fig. 8. Effect of window size and Levenshtein distance filtering for independent chemical mapping test set.

Extended Data Fig. 8

a) Calculating p(unpaired) using varying sliding windows of size 300, 600, and 1200 does not change the overall ranking obtained across datasets, compare to Fig. 4B, which was calculated for window size 900 (n=31 datasets for all). Package ranking is also consistent for a redundancy cutoff of 40% b) (n=16 datasets included after filtering based on 40% cutoff by windowed Levenshtein distance). Error bars in A and B represent 95% confidence interval for the mean Z-score as calculated by bootstrapping across respective number of datasets for each.